Samuel and Margaret Mosher were longtime supporters of UCSB. Samuel Barlow Mosher served as a UC Regent from 1956 until 1967, often flying Chancellor Vernon Cheadle to meetings of the regents in his own plane. He was an early and important donor to the present campus through the Samuel B. Mosher Foundation. In 1967, he contributed UCSB’s first major unrestricted gift ($93,937) and that followed a $100,000 gift in 1965 toward the building of the University Center (completed in 1966). By 1995, the Mosher Foundation had contributed over $2.1 million to UCSB for scholarships, athletics, buildings, and general use. He also made a significant donation to help build the University Religious Center in Isla Vista and the auditorium there was named in his honor in 1971. He was a graduate of UC Berkeley where he majored in agriculture. He was founder and owner of Signal Oil Company. However, orchid growing became his avocation and he founded Dos Pueblos Orchid Company in Goleta to pursue that interest. During World War II he was a director of the National Petroleum War Council. After the war, he was a founder and chairman of the board of the Flying Tiger Line.

Margaret Clinch Mosher was a trustee of The UCSB Foundation from 1983 until her death in 2002. She was named an Honorary Alumna of UCSB in 1992. She served as president of the Samuel B. Mosher Foundation and was president and owner of Dos Pueblos Orchid Company as well as owner of Perry Investment Company. She was also a board member of the Wilmer Eye Institute at Johns Hopkins University; the International Eye Tissue Bank; and the John Tracy Clinic, Los Angeles